PSV Eindhoven brushed aside Roda JC Kerkrade 3-0 to edge clear at the top of the Dutch league on Saturday.
PSV Eindhoven will miss striker Luuk de Jong when they entertain Atletico Madrid in the first leg of the Champions League last 16 on Wednesday.
Karim El Ahmadi struck twice as Feyenoord ended PSV Eindhoven's 39-match unbeaten run in all competitions with a 3-0 win in the quarter-finals of the Dutch Cup on Wednesday.
PSV Eindhoven's disappointing season took a turn for the worse as they went out of the Europa League after losing 1-0 at home to Ukrainians Chernomorets Odessa, who pipped them to second place in Group B on Thursday.
Real Madrid will play local rivals Atletico Madrid while Bayern Munich were drawn against Bundesliga title challengers Bayer Leverkusen on Friday.
Leicester City part ways with head coach Van Nistelrooy after Premier League relegation
Ajax Amsterdam have suspended their captain Luis Suarez for two matches after he bit PSV Eindhoven's Otman Bakkal on the shoulder during their 0-0 draw on Saturday.
Manchester United have appointed their former striker Ruud van Nistelrooy as an assistant to manager Erik ten Hag
Yildiz gave Juve the lead after 21 minutes with a stunning curling shot from just inside the box, leaving goalkeeper Joel Drommel helpless as the ball went in off the inside of the post.
Liverpool will start favourites but PSV Eindhoven coach Ronald Koeman will fancy another English scalp when the Dutch club host the first leg of their Champions League quarter-final on Tuesday.
Luuk de Jong scored a hat-trick and Memphis Depay netted the winner in the third minute of stoppage time as PSV Eindhoven beat Feyenoord 4-3 in a thrilling clash that put them four points clear on Wednesday.
An injury-time strike by Jonathan Reis sent PSV Eindhoven into the Europa League knockout rounds with a 1-0 home win over Sparta Prague on Thursday.
Real Sociedad scored two brilliant goals to win 2-0 against a stunned Olympique Lyonnais side who finished with 10 men while AC Milan held PSV Eindhoven to a 1-1 draw in Champions League playoff first legs.
PSV Eindhoven scored three second-half goals to beat Ajax Amsterdam 4-3 in a thrilling match and hand Martin Jol's team their first defeat of the Dutch league season on Sunday.
Ajax Amsterdam gave coach Martin Jol a winning start with a 2-0 success over Groningen in their opening game of the new Dutch league season on Sunday.
A summary of Wednesday's action in the UEFA Champions League Knock-out phase play-offs.
PSV Eindhoven are still looking for their first win of the season after sharing the points with Twente Enschede in a 1-1 draw in the Dutch league on Sunday.
But the 21-year-old is leaving sentiment behind in his new job with United, whose opening Group B game is at the Philips Stadium, and has no intention in following the trend of not celebrating scoring goals against former clubs.
Manchester United beat Lille 1-0 for a 2-0 aggregate win, while Bayern rallied from a 3-2 defeat to beat Real 2-1 and qualify on the away goals rule.
Luuk de Jong scored twice as champions PSV Eindhoven handed out a stark warning to the other Dutch league title contenders with a 3-0 win over Groningen in the Super Cup on Sunday.
A summary of Wednesday's action in the UEFA Champions League.
Liverpool shrugged off the absence of Mohamed Salah as midfielder Dominik Szoboszlai scored an 88th-minute penalty to give them a 1-0 Champions League win at Inter Milan.
Lionel Messi scored a record eighth Champions League hat-trick as Barcelona kick-started their campaign with a 4-0 home win over PSV Eindhoven, although they had defender Samuel Umtiti sent off late in the second half on Tuesday.
IMAGES from the UEFA Champions League last 16 matches played on Tuesday
Gakpo says Dutch skipper Van Dijk persuaded him to join Liverpool
A summary of Wednesday's Champions League Round of 16, Second Leg, matches.
A thrilling draw away to Salzburg enabled Serbian champions Red Star Belgrade to reach the Champions League group stage for the first time where they will be joined by Portugal's Benfica and Dutch side PSV Eindhoven. Red Star, who won the European Cup in 1991, came back from two goals down in an electrifying second leg in Austria to draw 2-2 and go through on away goals.
A summary of the UEFA Champions League Group Stage action, on Wednesday.
Mbappe fires Real Madrid to the summit, Bayern lose at home and Dortmund stay in the title hunt.
Luuk de Jong's early goal set PSV Eindhoven on their way to a 3-1 victory at Excelsior in the Dutch league that moved them to within one point of leaders Ajax Amsterdam
Inter Milan face Barcelona, Tottenham Hotspur and PSV Eindhoven in Group B which features three former European champions.
Manchester City came from behind to beat Club Brugge 3-1 and secure their place in the Champions League playoffs
IMAGES from the UEFA Champions League matches played on Wednesday
The first legs of the ties will take place on February 16, with the return match a week later on February 23.
Both managers have struggled in the Champions League this season, with PSG on seven points and 25th in the standings, one place outside the knockout phase playoff zone, while City are one point ahead in 22nd.
Argentina host Chile at the Monumental stadium in Buenos Aires on September 5 before facing Colombia five days later in Barranquilla.
Two goals by defender Daniel van Buyten, the second in stoppage-time, gave Bayern Munich a 2-2 draw against AC Milan in the first leg of their Champions League quarter-final.
Celtic, who won Europe's premier club competition in 1967, set up a clash with Romanians Cluj in the next stage after a 2-0 win at Nomme Kalju completed a 7-0 aggregate rout of the Estonian champions.
